WebChromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of … WebJun 2, 2024 · protamine deficiency by chromomycin A3 (CMA3) staining. In addition, the relationship between the fertilisation rate and sperm ubiquitination was calculated in ICSI candidates. The intensity of ubiquitination showed a significant negative correlation with sperm concentration (r = 0.255, P = 0.032) and a
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Chromomycin A3 (CMA3) or Toyomycin is an anthraquinone antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseus (No. 7). See more In the presence of Mg ions, Chromomycin A3 binds reversibly to DNA, preferentially to contiguous G/C base pairs. When bound to DNA, Chromomycin A3 has a maximum excitation wavelength of 445 See more • in-vitro membrane-impermeant G/C-specific fluorescent DNA-binding dye. • in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. • in-vitro anticancer drug that inhibits RNA synthesis. See more WebChromomycin A3 450 570 B, BV G-C Range 4, 6-Diamidino-2-Phenylindole HCl (DAPI) 372 456 U A-T Range Ethidium Bromide 545 605 G, IG DNA•RNA Hoechst 33258 365 465 U A-T Range Hoechst 33342 355 465 U A-T Range Mithramycin 395 570 BV G-C Range Olivomycin 430 ... dijigirls
Chromomycin A3 VWR
WebG-C specific intercalating agents [actinomycin D (AMD) and chromomycin A3 at 1 microM] also prevented ER disappearance; ethidium bromide (EB) and quinacrine were ineffective. AMD and CHX operated immediately after their addition to the medium indicating an inhibitory action on the synthesis of an RNA and/or a peptide with high turnover rate ... WebChromomycin A3 (CMA3) Protamination state of the spermatozoa determines its chromatin integrity status. The lesser the protamine content, the poorer the DNA packaging and the higher the sperm DNA damage. CMA3 binds to the sperm DNA deficient of protamine and stains light yellow [74]. The intensity of color is high in sperm with increased prot ... WebThe biosynthetic gene cluster of the aureolic acid type antitumor drug chromomycin A3 from S. griseus subsp. griseus has been identified and characterized. It spans 43 kb and … dijihu