List of platinum based chemotherapy agents

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August undefined, 2024

Web21 dec. 2024 · Platinum (Pt) agents, usually referring to carboplatin (Cb) and cisplatin (DDP), are cytotoxic DNA-damaging chemo-drugs widely used in various malignancies. Platinum can cause DNA strand... WebPlatinum agents are used to treat lymphomas, sarcomas, breast, colorectal, germ cell, ovarian, lung, gastro-oesophageal and bladder cancers. Most retrospective data …

Cytotoxic drugs Treatment summaries BNF NICE

WebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao … Web15 mei 2024 · The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is … dewayne miles football player west texas

New Platinum Drug Kills Cancer Cells Better - Medical News Today

Web10 nov. 2024 · Thus, associated with the use of platinum agents, expressed regression of the tumor process was observed in 36% of patients, compared with 14.9% of patients against the non-platinum chemotherapy. The results of linear regression analysis confirmed the statistical significance of this finding. WebOxaliplatin is platinum-based antineoplastic agent which has shown antitumor activity in a wide range of murine and human tumor cell lines in preclinical studies (Di Francesco et al., 2002). It has been approved for use in combination with 5-fluorouracil (5-FU) and folinic acid (FOLFOX regimen) for the therapy of advanced colorectal carcinoma ( Tesniere et al., … WebA list of chemotherapy drugs used to treat cancer. Click the drug name to learn how it works and common side effects. Skip Navigation. We value your privacy. Your user session will expire in 2 minutes. To stay logged in, please refresh the … church of scotland in decline

Platinum-based drugs: past, present and future - PubMed

Platinum-Based Antineoplastic - an overview ScienceDirect …

Web1 aug. 2007 · Key developments include the elucidation of mechanisms of tumour resistance to these drugs, the introduction of new platinum-based agents (oxaliplatin, satraplatin and picoplatin), and clinical combination studies using platinum drugs with resistance modulators or new molecularly targeted drugs. The accidental discovery of the … WebAsk a cancer patient and another use for platinum might come to mind – chemotherapy drugs. Platinum based chemotherapy is used to treat a variety of cancers and most often involves drugs like cisplatin, which is usually given as a drip into your bloodstream. These drugs work to destroy rapidly multiplying cells, like cancer cells. dewayne mcknight red hot chili peppersWeb17 jul. 2012 · Platinum-based chemotherapy drugs are among the most powerful and widely used against cancer. However, they have toxic side effects, and tumors can become resistant to them. church of scotland hymn book

"Web13 okt. 2024 · Platinum-based chemotherapy, including cisplatin, carboplatin, and oxaliplatin, is prescribed to 10-20% of all cancer patients. Unfortunately, platinum resistance develops in a significant... " - List of platinum based chemotherapy agents

List of platinum based chemotherapy agents

Ovarian Cancer Medication: Chemotherapy agents, Antineoplastic Agents …

Web14 mei 2024 · Patients enrolled in the study will be eligible to receive 4-6 cycles of platinum-based chemotherapy, and patients without progressive disease (PD) as per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 guidelines (i.e., with an ongoing complete response [CR], partial response [PR], or stable disease) after … Web• platinum-based chemotherapy regimens – containing a chemotherapy drug known as a “platinum agent” in combination with other chemotherapy drugs and; • non …

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Web4 apr. 2024 · Oxaliplatin (brand name: Eloxatin) is a platinum-based chemotherapy drug that works by disrupting DNA activity in the cancer cells to lead to cell toxicity and death. It is classified as an "alkylating agent". Oxaliplatin is given into a vein. It's used together with fluorouracil and leucovorin to treat more advanced colon and rectal cancer. Web21 sep. 2016 · Randomized phase II and III clinical trials comparing first-line palliative platinum-based chemotherapy with the same regimen without platinum or with platinum replaced by a nonplatinum agent were identified by electronic searches of Medline, Embase, and Cancerlit, and hand searches of relevant abstract books and reference lists.

WebPlatinum-based anticancer drugs, such as cisplatin, are standard chemotherapeutic agents in ovarian cancer therapy. Citation 39 , Citation 40 This class of drugs can penetrate the nucleus of cancer cells and form adducts with genomic or mitochondrial DNA to block the production of DNA, mRNA, and proteins, arrest DNA replication, and activate several … WebDepending on their characteristics and nature of treatment, chemotherapy agents can be categorized as alkylating agents, antimetabolites, anthracyclines, antitumor antibiotics, monoclonal antibodies, platinums, or plant alkaloids. Here, we discuss the main features of each of these categories. Alkylating agents

Web2 aug. 2024 · Taxane agents are used in the treatment of breast, gynecologic, prostate, head and neck, and lung cancers, and include paclitaxel, docetaxel, nab-paclitaxel, and cabazitaxel (Table 1) [ 15 ]. Paclitaxel (Taxol) was originally isolated from the bark of the Pacific yew tree, while docetaxel (Taxotere) was made from a semisynthetic process [ 15 ]. This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), … Meer weergeven • Altretamine • Bendamustine • Busulfan • Carboquone • Carmustine Meer weergeven • Ixabepilone Meer weergeven • Vorinostat • Romidepsin Meer weergeven • Etoposide • Teniposide • Tafluposide Meer weergeven Aclarubicin • Daunorubicin • Doxorubicin • Epirubicin Meer weergeven • Abraxane • Cabazitaxel • Docetaxel • Larotaxel Meer weergeven • Belotecan • Camptothecin • Exatecan • Gimatecan • Irinotecan • Topotecan Meer weergeven

Web2 mrt. 2024 · Among the women who received platinum-based combination chemotherapy for ovarian cancer, the relative risk of leukemia was 4.0 (95 percent confidence interval, 1.4 to 11.4). The relative risks for ...

WebIn this network meta-analysis, we found that patients who received a triple combination of platinum-based chemotherapy reported more hematological complications such as anemia and thrombocytopenia but provided relatively higher PFS and OS. In our study, all patients were sensitive to platinum-based chemotherapy during the first-line treatment. church of scotland hqWebPlatinum-based agents are important drugs or drug candidates for cancer chemotherapy. Traditional platinum drugs including the globally approved cisplatin, carboplatin and … dewayne maurice smith memphis policeWebPlatinum-based chemotherapy consisting of either cisplatin or ... antibody-dependent cell-mediated cytotoxicity. 8-10 It also enhances the activity of a number of chemotherapeutic agents, ... dewayne mills racingWeb28 mrt. 2024 · Zejula is indicated: • as monotherapy for the maintenance treatment of adult patients with advanced epithelial (FIGO Stages III and IV) high-grade ovarian, fallopian tube or primary peritoneal cancer who are in response (complete or partial) following completion of first-line platinum-based chemotherapy. church of scotland hymnsWebPlatinum compounds (e.g., carboplatin, cisplatin, oxaliplatin) have been central to the practice of oncology for the last 40 years.30 Cisplatin and carboplatin covalently bind to DNA causing intrastrand and interstrand DNA adducts. dewayne mcknightWeb14 apr. 2024 · Among 485 patients treated with first-line platinum-based chemotherapy, the probability of initiating maintenance avelumab increased over time following approval … church of scotland in the united statesWebModerately emetogenic treatment—the taxanes, doxorubicin hydrochloride, intermediate and low doses of cyclophosphamide, mitoxantrone, and high doses of methotrexate(0.1– … church of scotland investors trust forms